Soak it up. Grease is thick and likes to spread. To prevent this from happening, you have to stop the nasty stuff in its tracks. Pour talcum or baby powder over the oil slick to absorb the substance. Simply pour enough to completely cover the stain.
Wipe the powdery stuff off of your clothes after a minute or two. If the stain is large, place the garment down on a paper towel so that the stain makes contact with the towel. Blot the back of the stain with a dry-cleaning solvent. This clever trick will double-team the stain and send it on its way.
Spray all-purpose cleaner (think cleaners you can use on countertops and walls) on the annoying stain if it's still hanging around -- but only if your clothes are machine washable. All-purpose cleaners contain solvents that can cut through that disgusting grease. Leave the cleaner on the stain for a few minutes to let it work its magic. Avoid attempting to treat your dry-clean only clothes yourself. If these delicate garments experience staining, take them directly to the dry-cleaners -- applying any substances to such clothes can cause serious damage to your duds.
Rinse the cleaner off of the stain site with warm water once it dries and the stain is history. Since some stains can be stubborn little buggers, you may have to treat the grease a few times before it is completely gone, especially if the stain is old.
Lay the garment flat and allow it to air-dry. Tossing it in the dryer can sometimes aggravate the stain and cause it to return or permanently set in.
If you don't have any cleaner around, douse the stain with dishwashing soap. Allow it to sit on the grease for about five minutes, then blot it with a paper towel. Rinse the sudsy stuff off with water and throw it in the washer.